UNIVERSITAS AIRLANGGA



Detail Article

Media Kedokteran Hewan

ISSN 2015-8930

Vol. 27 / No. 1 / Published : 2011-01

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Original Article :

superoxide dismutase (sod) activity and histological pancreas of type 1 diabetes mellitus rats which get the temu giring (curcuma heyneana) extract treatment

Author :

  1. Aulanni’am*1

Abstract :

Diabetes mellitus (DM) is often referred to as the great imitator. This is due to DM disease can cause organ damage as a whole is anatomically and functionally. One alternative treatment of diabetes mellitus is by using herbal therapy temu giring (Curcuma heyneana) rhizome extract. This study aimed to describe the ability of rhizome extract temu giring (Curcuma heyneana) in increasing SOD activity and improve pancreatic tissue damage of DM rats induced by MLD-STZ. In this study used an animal model of type I diabetic rats by giving Multiple Low-Dose Streptozotocin (MLD-STZ) dose of 20 mg/kgBW for 5 consecutive days. Temu giring extract as an alternative therapy is given to trial animals with varying doses of 1.25, 2.5 and 3.75 g/kgBW for 7 consecutive days. The results showed that rhizome extract therapy temu giring doses of 1.25, 2.5 and 3.75 g/kgBW in rats induced by MLD-STZ showed increased SOD activity in succession at 29.42%, 52.30% and 80.16%, and repair damage to pancreatic tissue. Maximum therapy in type 1 diabetic rats are shown in the temu giring extract dose 3.75 g/kgWB.

Keyword :

DMtype1, MLD-STZ, Temugiring(Curcuma heyneana),


References :





Archive Article

Cover Media Content

Volume : 27 / No. : 1 / Pub. : 2011-01
  1. Superoxide Dismutase (sod) Activity And Histological Pancreas Of Type 1 Diabetes mellitus Rats Which Get The Temu Giring (curcuma Heyneana) Extract Treatment
  2. Inhibin B Decrease The Amount Of Infant Rats (rattus Norvegicus) Of In Vivo Fertilization By Reversible: A Development Of Male Contraceptive Based On Peptide Hormones
  3. The Role Of Aspergillus Niger In Increasing Putak Protein Content
  4. Ingredient Of Lean Beef Extract, Small Green Pea Kernel And Chicken’s Bile Liquid As Selective Medium For Gram Negative Bacteria Derived From Intestine
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  7. Rapid Diagnosis Of Avian Influenza Virus A Subtype H5n1 Isolates From Disease Investigation Center (dic) Wates Using Single Step Multiplex Rt-pcr Method
  8. Study Of Rabies Antibody Titters On Dogs Which Are Transported Through Merak Port
  9. Detection Of Outer Membrane Protein (omp) Cell Wall Of Brucella Abortus Local Isolate By Polymerase Chain Reaction (pcr) As Brucellosis Vaccine Candidate
  10. The Effect Of Vitamin D3 On Structural Microscopic Of Ischium Bones In Ovariectomized Rats
  11. The Effect Of Addition Insulin Like Growth Factor-i Complex From Goat Seminal Plasm In Medium Centrifugation To Reactive Oxygen Spesies (ros) Concentrate Of Sperm
  12. Histopathological Changes Of The Femur Of Panhisterectomized Sprague Dawley Rats Fed High Phosphorous Diet
  13. Dry Matter And Crude Protein Intake Of Sheep Fed Lignocellulolytic enzymes Treated Waste Agroindustrial

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