Media Kedokteran Hewan
ISSN 2015-8930
Vol. 19 / No. 1 / Published : 2003-04
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Original Article :
The microscopic structure of ischium bones in ovariectomized rats with high ratio phosphate/calcium feeding
Author :
- Dian Masyitha*1
- Laboratorium Histologi Fakultas Kedokteran Hewan Universitas Syiah Kuala
Abstract :
This experiment was conducted to study the microscopic structure of bones in ovariectomized rats with ratio phosphate/calcium feeding. Fifteen female Sprague Dawley rats 7 weeks old were randomly divided into 3 groups. The rats in the control group (non-ovariectimized). The rats in group II and III were ovariectomized. Phosphate/calcium diet were fed with ratio of 2 to 1 (K1, K2) and 6 to 1 (K3). After 12 weeks the rats were sacrificed. The ischium bone were collected and processed for microscopic examination with trichrome staining. The results showed that structurally the osteoporosis occurred in ischium bone of group K2 and K3. It could be concluded that estrogen deficiency condition (ovariectomy) and high ratio phosphate/calcium ration caused osteoporosis in ischium bones.
Keyword :
Osteoporosis, ovariectomy, ischium bones, high ratio phosphate/calcium feeding ,
References :
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