UNIVERSITAS AIRLANGGA



Detail Article

OVOZOA

ISSN 2302-6464

Vol. 2 / No. 2 / Published : 2013-10

Order : 10, and page :74 - 81

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Original Article :

Effect of infusum salam leaves (eugenia polyantha) testis spermatogenic cells amount of white rats (rattus norvegicus) induced alloxan

Author :

  1. Gahastanira*1
  2. Wurlina *2
  3. Abdul Samik *3
  4. Budiarto *4
  1. Mahasiswa Fakultas Kedokteran Hewan Unair
  2. Departemen Reproduksi Veteriner Fakultas Kedokteran Hewan Unair
  3. Departemen Reproduksi Veteriner Fakultas Kedokteran Hewan Unair
  4. Departemen Kesehatan Masyarakat Veteriner Fakultas Kedokteran Hewan Unair

Abstract :

This research was aimed to know the effect of infusum salam leaves (Eugenia polyantha) on the appearance of testicular spermatogenic cells white rats (Rattus norvegicus) with diabetes mellitus. A number of 25 white rats (Rattus norvegicus) strain Wistar were divided into 5 groups. The pancreas of 4 groups was damaged using a doses of alloxan 200 mg/kg intraperitoneally. After state hyperglycemia condition, 3 groups was treatment with a dose therapy of infusum salam leaves (P1) 412.5 mg/150gbb, treatment (P2) 825 mg/150gbb and treatment (P3) 1237.5 mg/150gbb dose, one group as a control negative as the normal group and one group as a control positive was induced with alloxan but without infusum salam leaves treatment. The treatment was for 48 days,  the mice were killed and were taken the testes organs to made a histopathology preparations using Hematoxylin-eosin staining (HE). The result of the study showed that infusum salam leaves (Eugenia polyantha) giving on treatment groups led to an increase in the number of spermatogenic cells (p <0.05) at all doses compared to positive controls. Treatment (P3) 1237.5 mg/150gbb dose can increase the amount of the highest spermatogenic cells.  

Keyword :

diabetes mellitus, alloxan, infusum salam leaves, spermatogenic cells,


References :

Nugraheni, T., P. A. Okid dan T. Widiyani. ,(2005) Pengaruh Vitamin C terhadap Perbaikan Spermatogenesis dan Kualitas Spermatozoa Mencit (Mus musculus L.) Setelah Pemberian Ekstrak Tembakau (Nicotiana tabacum L.). Jakarta. : Biofarmasi. 1 (1): 13-19.

Nijveldt, R. T., N. Van., D. E. C. V. Hoorn, P.G. Boelens., K. V. Norren and P.A.M. V. Leeuwen. ,(2001) Flavonoids: A review of probable mechanism of action and potential applications. USA : Am. J. Clin. Nutr. 74: 418-425.





Archive Article

Cover Media Content

Volume : 2 / No. : 2 / Pub. : 2013-10
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  2. Effect Of Different Injection Time Of Pregnant Mare Serum Gonadotropin (pmsg) On The Onset Of Estrous Of Fat Tailed Ewes Synchronized Using Intravaginal Progesterone
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  4. Effect Of Glycerol In Skim Egg Yolk Diluent On The Freezing Of Goldfish Spermatozoa (cyprinus Carpio)
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  8. Reproductive Efficiency Of Beef Cattle Resulted From Artificial Insemination In Wringin Subdistrict, Bondowoso District In 2012
  9. Artificial Insemination Program For Beef Cattle In Madura Island “targets, Realisation And Problems”
  10. Effect Of Infusum Salam Leaves (eugenia Polyantha) Testis Spermatogenic Cells Amount Of White Rats (rattus Norvegicus) Induced Alloxan
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  13. Effect Of Seminal Plasm Of Cow On Goat’s Spermatozoa Motility And Viabilityin In Milk Diluter
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