OVOZOA
ISSN 2302-6464
Vol. 6 / No. 2 / Published : 2017-10
Order : 6, and page :111 - 115
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Original Article :
Pengaruh ekstrak daun lampes (ocimum sanctum linn) terhadap motilitas dan viabilitas spermatozoa mencit (mus musculus)
Author :
- Mirna Triastuty*1
- Prof. Mas’ud H., drh., M.Phil., Ph.D.*2
- Dr. Dady S. Nazar, drh., M.Sc.*3
- Mahasiswa Fakultas Kedokteran Hewan
- Dosen Fakultas Kedokteran Hewan
- Dosen Fakultas Kedokteran Hewan
Abstract :
Lampes, also known as Holy basil (Ocimum sanctum Linn) has many medicinal properties, including antifertility effect. This research was aimed to determine the effects of Ocimum sanctum L. leaf extract on spermatozoa motility and viability of mice (Mus musculus). Twenty four male mice were divided into four groups. Mice from control group were only given aquadest, mice from treatment groups were given 125, 250, and 500 mg/KgBW/day of Ocimum sanctum L. leaf extract for 10 days orally by inserting the gastric tube directly into the gastric of mice. At the end of the treatments, mice were euthanized and the testes were taken. After semen collected, the observations of spermatozoa motility and viability were done. Data was analyzed by ANOVA and continued with Tukey test. Research result showed there were significant differences (p<0.05) among the treatment groups. The highest reduction of spermatozoa motility and viability was reached by the administration of 500 mg/kgBW/day of Ocimum sanctum L. leaf extract. In conclusion, Ocimum sanctum L. leaf extract decreased spermatozoa motility and viability of mice (Mus musculus).
Keyword :
Mus musculus, Ocimum sanctum L., spermatozoa motility, spermatozoa viability,
References :
Ampofo-Yeboah, A., H. Lambrechts, D. Brink, F. Hiten and E. Afriyie-Gyawu. ,(2013) Analysis of Oleanolic Acid and Ursolic Acid, Potential Antifertility Agents in Moringa (Moringa oleifera) Seed. A 3: 989-999. : Journal of Agricultural Science and Technology
Joshi, S.C., A. Sharma and M. Chaturvedi. ,(2011) Antifertility Potential of Some Medicinal Plants in Males: An Overview. International 3: 204-217. : Journal of Pharmacy and Pharmaceutical Sciences,
Pragya, S., A.R. Hembram and V.N. Singh. ,(2012) Antifertility Effects of Aqueous Leaf Extract of Ocimum sanctum Linn (Tulsi) On Seminal Profile of Mice. 7(2): 275-276. : An International Quarterly Journal of Life Sciences.
Shama, S.N.,(2012) A Mine of Medicinal Uses: Ocimum sanctum, the Holy Basil. 2. Issue 2: 69-74. : International Journal of Pharmacy Review & Research.
Archive Article
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