Veterinaria Medika
ISSN 1979-1305
Vol. 6 / No. 1 / Published : 2013-02
Order : 2, and page :5 - 8
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Original Article :
Injection effect of mice (mus musculus) testes and spleen homogenat derived hy-antigen on pup’s sex ratio
Author :
- Srianto, Pudji*1
- Nilasari, A.N*2
- Anwar, Husni*3
- Narumi, Hasutji Endah*4
- Fakultas Kedokteran Hewan Universitas Airlangga
- PPDH Fakultas Kedokteran Hewan Universitas Airlangga
- Fakultas Kedokteran Hewan Universitas Airlangga
- Fakultas Kedokteran Hewan Universitas Airlangga
Abstract :
HY-antigen is the first plasma membrane that plays a role in the process of organogenesis.The functions of HY-antigen are to stimulate immune response of T lymphocyte and the developing of genital ridge into testes. This research was aimed to determine differences in sex ratio of mice which had been injected by HY-antigen. The first treatment (P1) was the HY-antigen that was derivedfrom mice testes homogenate and the second treatment (P2) was the HY-antigen that was derivedfrom mice spleen homogenate. The data was analyzed by independent T test and the result showed that there was no significant difference between the two treatment (P>0,005). Those two treatments were able to skew the sex ratio towards males.
Keyword :
HY-antigen, Organogenesis, Testes, Spleen, Mice,
References :
Andonian, L., M. B. Eslami, A. A. Mohammad, J. Akbarzadah, H. R. Soelaimanpour, and D. D. Farhad.,(2001) Preparation of HY Antibody in Female Mice as a Model for Sex Preselection. Iranian : Iranian J. Publ Health. 30. 41-44.
Arsov I and Vukmanovic S.,(1997) ltered Effector responses of HY Transgenic CD8+ cells. . : International Immunology. 9: 1423-1430.
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