Jurnal Respirasi
ISSN 2407-0830
Vol. 1 / No. 2 / Published : 2015-05
Order : 5, and page :67 - 71
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Original Article :
Biomarker pernapasan pada penyakit paru
Author :
- Novita Maulidiyah, dr*1
- Prof. Dr. Muhammad Amin, dr., Sp.P(K)*2
- Mahasiswa Fakultas Kedokteran
- Dosen Fakultas Kedokteran
Abstract :
Breath analysis provides a convenient and simple alternative to traditional specimen testing in clinical laboratory diagnosis. As such, substantial research has been devoted to the analysis and identiï¬cation of breath biomarkers. Development of new analytes enhances the desirability of breath analysis especially for patients who monitor daily biochemical parameters. Elucidating the physiologic signiï¬cance of volatile substances in breath is essential for clinical use. This review describes the use of breath biomarkers in diagnosis of asthma, chronic obstructive pulmonary disease (COPD), cystic ï¬brosis (CF), lung cancer, as well as other pulmonary diseases. A number of breath biomarkers in lung pathophysiology will be described including nitric oxide (NO), carbon monoxide (CO), hydrogen peroxide (H2O2) and other hydrocarbons.
Keyword :
nitric oxide, hidrogen peroxide, pulmonary disease,
References :
Meigu Z, smith AD,(2012) breath biomarker in diagnosis of pulmonary disease - : Clinical Chimica Acta
Raed A, Dweik, Peter B,(2011) interpretation of exhaled NO levels (Feno) for clinical application - : ATS




