UNIVERSITAS AIRLANGGA



Detail Article

Majalah Ilmu Faal Indonesia

ISSN 0215-1995

Vol. 9 / No. 2 / Published : 2010-02

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Original Article :

the effect of one session physical exercise to interleukin 6 and von willebrand factor blood level in white rat (rattus novergicus strain wistar)

Author :

  1. Afriwardi*1

Abstract :

Heavy physical exercise presumed to cause some changes in endothelial cells through physical and chemical trauma. This research was aimed to assess the influence of one physical exercise session to Interleukin-6 (IL-6) and von Willebrand Factor (vWF) as one of parameters for endothelial cells damage level. This  research is a true experimental study with one way full randomized design. Forty white rats (Rattus novergicus strain wistar) are divided into 4 groups, each contain 10 rats. The first group is given one light physical exercise session (group P1), the second groups given one session of moderate physical exercise (group P2), the third group is given one session of heavy physical exercise (group P3), and the last group is control. After intervention, the IL-6 and vWF blood concentration of the rats was measured by ELISA technique using R&D system’s kit. The difference of average blood concentration between groups were analyzed by ANOVA test continued by Benferroni. The result showed that significant difference of average IL-6 and vWV concentration between groups. The average of  IL-6 (K:48.570±28.337 áµ–g/ml; P1: 71.362±48.812 áµ–g/ml; P2: 96.076±50.080 áµ–g/ml; P3: 142.298±78.289 áµ–g/ml) with p value = 0.003 (p< 0.05) meanwhile for vWF (K:160.111±87.664 áµ–g/ml; P1: 198.042±76.738 áµ–g/ml; P2: 281.707±143.890 áµ–g/ml; P3: 282.916±78.467 áµ–g/ml) with p value = 0.042 (p<0.05). After continuing with Post Hoc analyze, there is significant difference between control group and the third group for IL-6 (p= 0.008), meanwhile there is no significant difference for vWF ( p>0.05). In conclusion, there was significant improvement of IL-6 but not with vWF blood level after giving one session of heavy physical exercise.  

Keyword :

Interleukin-6, von Willebrand Factor , physical exercise,


References :





Archive Article

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Volume : 9 / No. : 2 / Pub. : 2010-02
  1. immune reaction to the eating and drinking fasting induced stress
  2. a new concept of chronic heart failure
  3. the effect of giving lidah buaya (aloe vera) juice to decrease amount of blood glucose and triglycerides in rattus norvegicus induced by alloxan
  4. the effect of leaf katuk powder (sauropus androgynus) in broiler chicken feeding in feed digestibility, bodyweight, and bile production
  5. polymorphisms of t/c 8002 endothelin-1 gene, body mass index and gestational hypertension
  6. effect of plasma angiotensin converting enzyme (ace) in erectile dysfunction
  7. anti diabetic effects of boiled sea jujube on white rats induced alloxan
  8. myoglobin gene expression of soleus, gastrocnemius and cardiac muscles after aerobic and anaerobic exercise in wistar rat
  9. the effect of one session physical exercise to interleukin 6 and von willebrand factor blood level in white rat (rattus novergicus strain wistar)
  10. the effect of active recovery in warm water on the reduction of post-exercise blood lactic acid concentration on white rat (rattus norvegicus)
  11. The effect of regular exercise and estrogen replacement therapy on the duration of heart’s muscle repolaritation after bilateral ovariectomized sprague dawley mice
  12. The application of ergonomical aspect in sport : the influnce of the length of the hand to the distance of the toss in sma i kediri tabanan students

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