UNIVERSITAS AIRLANGGA



Detail Article

Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 16 / No. 1 / Published : 2009-11

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Original Article :

Analysis of uric acid level in patients of carcinoma mammae

Author :

  1. Susi Sevianty*1
  2. Uleng Bahrun*2
  3. Mansyur Arif*3
  1. Departemen Patologi Klinik FK Universitas Hasanuddin – RS Dr. Wahidin Sudirohusodo Makassar
  2. Departemen Patologi Kinik FK - UNHAS - RS. Dr. Wahidin Sudirohusodo Jl. Perintis Kemerdekaan Km 10 Talamarea Makassar
  3. Departemen Patologi Kinik FK - UNHAS - RS. Dr. Wahidin Sudirohusodo Jl. Perintis Kemerdekaan Km 10 Talamarea Makassar

Abstract :

In malignancy cases, an increase of uric acid level is often observed after therapy (Tumor Lysis Syndrome), but some studies also indicated an increase before therapy which is related to a refusal reaction against tumor, and specific only for certain malignancy cases. Carsinoma mammae is the second most common malignancy among women in Indonesia, so that studying the phenomenon occurred in carcinoma mammae including uric acid level are expected to provide insight in management of carcinoma mammae. A longitudinal study was conducted by collecting secondary data from medical record of carcinoma mammae patients in Wahidin Sudirohusodo Hospital for period of July 2007–June 2008. Data were analyzed by using Wilcoxon Signed Rank Test with alpha 0.05. 12 of subjects are considered eligible for study criteria, with the age ranging from 28–60 years old. In generally, uric acid level determined before and after chemotherapy showed a level in normal range, except for 3 samples before therapy and 3 different samples after therapy showed a level more than 5.7 mg/dL. Statistic result showed mean uric acid level before chemotherapy was 4.508 ± 1.2566 mg/dL and after chemotherapy was 5.025 ± 1.3240 mg/dL (p = 0.16). Increased of uric acid level is not significant level was found in serum of carcinoma mammae before and after chemotherapy.

Keyword :

Carcinoma mammae, uric acid,


References :

Sukardja IDG,(1996) Neoplasia Jakarta : EGC





Archive Article

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Volume : 16 / No. : 1 / Pub. : 2009-11
  1. Homolog legionella pneumophila distribution and nosocomial pneumopniae
  2. Diagnostic value of malaria antigen cassette on malaria disease
  3. Cd4 analysis in treatment of hiv-tb co-infected patients
  4. Analysis of uric acid level in patients of carcinoma mammae
  5. Anti hcv and the patient’s prevalence of virus hepatitis c infection
  6. The evaluation of transaminase activities, and bilirubin level in patients with hepatitis b virus and c virus
  7. Correlation degree of non-alcoholic fatty liver with aminotransferase serum activity
  8. Accuracy of bactident aminopeptidase test in identification gram negative bactery)
  9. Study of cd38 expression on lymphocyte 8+, cd4+ profile, and clinical state immunological and clinical state profile of aids/hiv patients with antiretroviral therapy)
  10. Eosinofil after mucosal nasal brushing and routine hematology in allergy rhinitis
  11. Normoblast counting between acute myeloblast leukemia and acute lymphoblastic leukemia in peripheral blood smear of patients
  12. Measurement and clinical application of thrombin activatable fibrinolysis inhibitor
  13. Abnormal trombosit in post-partum
  14. Laboratory costing per test based on jaros ml method

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