UNIVERSITAS AIRLANGGA



Detail Article

Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 15 / No. 3 / Published : 2009-07

Related with : Scholar   Yahoo!   Bing

Original Article :

Inflammatory marker hs crp with hipertension

Author :

  1. Suswanto*1
  2. Siti Muchayat P.*2
  1. Departemen Patologi Klinik Fakultas Kedokteran Universitas Gajah Mada Jogyakarta
  2. Departemen Patologi Klinik Fakultas Kedokteran Universitas Gajah Mada Jogyakarta

Abstract :

The major pathophysiologic mechanisms of hypertension include the activation of sympathetic nervous system and rennin–angiotensin–aldosterone system. Endothelial dysfunction, increased vascular reactivity, and vascular remodeling may cause that matter, rather than its consequences, of blood pressure elevation; increased vascular stiffness, which contributes to isolate systolic hypertension in the elderly persons. Chronic low grade inflammation has been identified as an integral part in the pathogenesis of vascular disease. Inflammation may also be implicated in the development of hypertension. Several studies have demonstrated a significant relationship between hs-CRP and stiffness of large arteries. If inflammation is truly linked to hypertension, then it would be reasonable to assume that drugs with anti-inflammatory actions may be able to arrest inflammation, improve endothelial function and lowering blood pressure in patients with hypertension. The aim of this cross sectional design study is to observe high sensitive C-reactive protein (hs-CRP) inflammatory markers in thirty five patients with hypertension. also want to know the present correlation between marker inflammation hs CRP with hypertension. With examine to some confounding factors as LDL, GDR and WBC. The results of this study showed that there is no correlation between hs-CRP and hypertension, especially the duration of hypertension (r = 0.5 and p = 0.002). High degree of hypertension was not followed by the increasing level of hs CRP.

Keyword :

Hypertension, inflammatory marker, inflammation, hs-CRP,


References :

Armilawaty, Husnul A, Ridwan A,(2007) Hipertensi dan faktor risikonya dalam kajian epidemiologi Makassar : FKM UNHAS





Archive Article

Cover Media Content

Volume : 15 / No. : 3 / Pub. : 2009-07
  1. Cd4 cell counts with igm herpes simplex-type 2 in hiv patients
  2. The transferrin saturation profile among anaemic blood donors
  3. Iron deficiency anemia of babies
  4. Patients’ serum protein electrophoresis with normal serum total protein level
  5. Inflammatory marker hs crp with hipertension
  6. Comparison of kalium serum level with or without insulin therapy at type 2 diabetic mellitus patiens
  7. Microalbuminuria of type 2 dm patients
  8. Analysis of the immunochromatography and enzyme-linked immunosorbent assay tests to diagnose helicobacter pylori in dyspepsia
  9. Soluble transferrin receptor level in human immunodeficiency virus/acquired immunodeficiency syndrome patients with anemia
  10. Comparison of specthrophotometer method with hemocue method for haemoglobin measurement in leucocytosis sample
  11. Toll-like receptor (tlr) and natural immunity
  12. A retinoid acid receptor in acute promyelocytic leukemia auer rods
  13. Errors during clinical laboratoric procedures

Information CPML