UNIVERSITAS AIRLANGGA



Detail Article

Media Kedokteran Hewan

ISSN 2015-8930

Vol. 23 / No. 3 / Published : 2007-08

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Original Article :

Bcg vaccination increased roi secretion in dogs macrophage infected with mycobacterium tuberculosis

Author :

  1. Ida Tjahajati*1
  1. Bagian Ilmu Penyakit Dalam, Fakultas Kedokteran Hewan, Universitas Gadjah Mada,Jl. Olah Raga, Karang Malang Yogyakarta 55281, Hp:081578890500

Abstract :

The aim of this experiment is to study the effect of BCG vaccination on ROI secretion activity in dog peritoneum macrophage which infected with M. tuberculosis. The experiment used twenty four healthy dogs. The animals were divided in 2 groups, 12 dogs in each group . Group I were vaccinated by BCG, group II were control group which unvaccinated. BCG vaccination was done twice with two weeks interval. Two days after vaccination each dog was infected by 104 cfu M. tuberculosis intraperitoneally. The activity of macrophages were measured at 1st, 2nd, 12th, and 24th, after infection using NBT reduction assay. Three dogs were used to measure the macrophage activity in each period, using triplicate sample for each dog. The results of the experiment showed that the ROI secretion increased significant deference in vaccination group (P

Keyword :

BCG, ROI, M. tuberculosis, dogs,


References :

K Djamiatun,(0000) Pengaruh vitamin A dan BCG pada produksi TNF-α dan aktivitas fagositosis makrofag terhadap Staphylococcus aureus. Laporan Akhir Tahun I Risbin Iptekdok. - : Laporan Akhir Tahun I Risbin Iptekdok

Muthmainah,(2002) Studi tentang aktivitas makrofag mencit yang distimulasi dengan protein soluble Toxoplasma dan BCG selama infeksi Toxoplasma gondii. Thesis. Program Studi Ilmu Kedokteran Tropis. Pascasarjana. Yogyakarta : Universitas Gadjah Mada Yogyakarta

A Nikmawati,(2006) Resistensi Mycobacterium tuberculosis terhadap obat anti tuberkulosis - : Indonesian Journal of Clinical Pathology and Medical Laboratory. 12 (2)

Siswono,(2006) Jumlah Penderita Tuberkulosis di Indonesia Nomer Tiga di Dunia. http://www.mediaindo.co.id - : http://www.mediaindo.co.id

I Tjahajati,(2004) Profil sitokin Th1-Th2 terhadap infeksi M.tuberculosis pada kucing - : Media Medika Indonesiana. 39 (3)

I Tjahajati,(2004) Aktivitas sekresi reactive oxygen intermediate (



Archive Article

Cover Media Content

Volume : 23 / No. : 3 / Pub. : 2007-03
  1. Cecal goblet cell response on intracellular development of eimeria tenella in susceptible and infected chickens
  2. Protein characterization of snail mucin (achasin) local isolate as an antibacterial factor
  3. Trypsin and pronase treatment on the development of mouse embryos contaminated by k99 escherichia coli
  4. The optimation of tyrosine kinase activity from sperm isolation of friesian holstein cow
  5. Insulin-like growth factor i (igf-i) complex seminal plasma of goatratio glicoprotein : protein : carbohydrate
  6. The role of choline esterase on vesicle brain development of chicken embryo of exposure by carbofuran insecticide
  7. Marker-sets for paternity and identity test in pigs by meansmicrosatellite analysis
  8. Bcg vaccination increased roi secretion in dogs macrophage infected with mycobacterium tuberculosis
  9. Antifertility effect of aqoueus extract betel nut of areca catechu: as an apoptosis agent on testis connective cells of rattus norvegicus
  10. The morphology of mandibular and lingual glands of chicken (gallus sp) and quail (coturnix coturnix): with special refference to the distributionand carbohydrate content
  11. Detection of rabies virus in saliva and brain using antibody from g protein as material diagnostic by indirect double antibody sandwich elisa technique
  12. Study to rice brand in drying ensilage product from edible snail for decrease higroscopies as feed stuff
  13. Potency rice straw was deammoniated and fermented by celulolytic bacteria on the dry matter consumption, body weight gain and feed conversion of sheep
  14. Cecal goblet cell response on intracellular development of eimeria tenella in susceptible and infected chickens
  15. Protein characterization of snail mucin (achasin) local isolate as an antibacterial factor
  16. The role of choline esterase on vesicle brain development of chicken embryo of exposure by carbofuran insecticide
  17. The optimation of tyrosine kinase activity from sperm isolation of friesian holstein cow
  18. Insulin-like growth factor i (igf-i) complex seminal plasma of goat ratio glicoprotein : protein : carbohydrate
  19. Marker-sets for paternity and identity test in pigs by means microsatellite analysis
  20. Bcg vaccination increased roi secretion in dogs macrophage infected with mycobacterium tuberculosis
  21. Antifertility effect of aqoueus extract betel nut of areca catechu: as an apoptosis agent on testis connective cells of rattus norvegicus
  22. Trypsin and pronase treatment on the development of mouse embryos contaminated by k99 escherichia coli
  23. The morphology of mandibular and lingual glands of chicken (gallus sp) and quail (coturnix coturnix): with special refference to the distribution and carbohydrate content
  24. Detection of rabies virus in saliva and brain using antibody from g protein as material diagnostic by indirect double antibody sandwich elisa technique
  25. Study to rice brand in drying ensilage product from edible snail for decrease higroscopies as feed stuff
  26. Potency rice straw was deammoniated and fermented by celulolytic bacteria on the dry matter consumption, body weight gain and feed conversion of sheep
  27. Cecal goblet cell response on intracellular development of eimeria tenella in susceptible and infected chickens

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